Dr Sarah Brüningk

The Institute of Cancer Research

Sarah completed a M.Sc. in Physics (Biophysics) at the Technische Universität München with the major focus on bio-medical and soft matter physics. Having worked in a medical physics group throughout her degree, she joined the clinical medical physics staff in the radiotherapy department at the Klinikum rechts der Isar in Munich until starting a PhD at the Institute of Cancer Research in October 2014. Her PhD focused on modelling and quantifying biological response to combination treatments of focused ultrasound mediated hyperthermia and radiotherapy. Since 2018 Sarah has been working as a Post Doctoral Training Fellow at the Institute of Cancer Research working on biology guided treatment planning for multimodality therapies.

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The role of ultrasound therapy in cancer treatments

Therapeutic ultrasound is a non-invasive, localized technique to deliver heating and/or mechanical stress deep into tissue. Applications for cancer therapy range from pain palliation to disease eradication using a variety of techniques including hyperthermia, drug delivery enhancement, ablation (of tumour or nerves), and mechanical tissue disruption (histotripsy). It can be deployed either as single modality or in combination with other treatments, such as radiotherapy.