Prof James O’Connor

University of Manchester / Cancer Research UK / The Christie

James O’Connor is Professor of Radiology at The University of Manchester, UK and a Cancer Research UK (CRUK) Advanced Clinician Scientist Fellow. He is also an Honorary Consultant in Radiology at The Christie NHS Foundation Trust, Manchester, UK, where he specialises in cross-sectional and functional imaging. He co-leads the CRUK National Cancer Imaging Translational network that links seven leading centres of cancer imaging research together in the UK.

He graduated in medicine from the University of Cambridge, UK, and University of London, UK. He completed a PhD on imaging biomarkers in cancer and is an international authority on the development and translation of MRI biomarkers radiobiology from laboratory to clinic. Current research focuses on using biomarkers to guide decision making in early phase clinical trials of drug-radiation combinations, including hypoxia modification, targeting angiogenesis and modulating tumour immunology.

dont miss

Developing a new MRI method of tracking hypoxia in cancer

Oxygen deprivation (hypoxia) causes treatment resistance and poor clinical outcome in most solid tumours. Imaging methods are required to identify, quantify and track change in hypoxia, while also being cost-effective and readily available to healthcare providers. This seminar describes the emerging technology ‘Oxygen-enhanced MRI’. Current evidence that this technology detects and maps radiation- and drug-induced hypoxia modification are discussed along with future applications such as guiding adaptive radiotherapy planning.


  • Dr Ai Lyn Tan: Speaking at the Medical Imaging Convention

    Dr Ai Lyn Tan
    NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, and University of Leeds

    How imaging has enhanced knowledge about rheumatic diseases

  • Dr Scott Semple: Speaking at the Medical Imaging Convention

    Dr Scott Semple
    University of Edinburgh

    Magnetic Resonance Imaging of myocardial viability

  • Dr Heather E. L. Rose: Speaking at the Medical Imaging Convention

    Dr Heather E. L. Rose
    The University of Birmingham

    MR imaging and Spectroscopy of Paediatric Brain Disease

  • Dr Anna Barnes: Speaking at the Medical Imaging Convention

    Dr Anna Barnes
    University College Hospital

    Imaging biomarkers to investigate neuropathology

  • Dr Nasir Hameed: Speaking at the Medical Imaging Convention

    Dr Nasir Hameed
    School of Medicine, University of Central Lancashire

    Remote Imaging ‘Pass me my stethoscope – I mean smartphone’